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Author Topic:   Hair Cell Research-A cure?
Jon
unregistered
posted 07-18-2001 10:15 AM           Edit/Delete Message
Dear All,

Below is the reply I've just received back from Otogene.
Sounds promising!

Jon

**********************
Tübingen, 18 July 2001

Thank you very much for your interest in OTOGENE AG and its research in hearing loss.

It is true that OTOGENE AG intends to develop a drug for the treatment of sensorineural hearing loss (SNHL), which is caused by the loss of the sensory cells in the inner ear (termed hair cells). SNHL can be caused by ageing, noise or toxic effects. While we have made significant scientific progress in animal models since OTOGENE AG was formed in 1998, we still do not have drug candidates available for testing in humans.

We hope to enter clinical trials in early 2004 and to be on the market by 2008 with a first product that improves hearing. We will update our website www.otogene.de regularly to report on scientific news.


With the kindest regards

Hans-Jörg Bergler

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Bob
Member
posted 07-19-2001 01:04 PM     Click Here to See the Profile for Bob     Edit/Delete Message
Hi everyone,

I just came across a recent article in the Seattle times on the research being done at the University of Washington.
http://archives.seattletimes.nwsource.com/cgi-bin/texis/web/vortex/display?slug=hear01m0&date=20010701&query=Warren+King

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HHIssues
Member
posted 07-22-2001 03:14 PM     Click Here to See the Profile for HHIssues     Edit/Delete Message
Hello everyone,

Just wanted to let you know that I sent an e-mail to the program, ScienceFriday. Asking if they could possibly do a segment on Hair cell regeneration. After all, every little bit helps or counts. Just as long we're planting the seeds for the future, etc. Right ?

<--- Start of e-mail --->

Subject: Why don't you do a show about....

Hair Cell Regeneration !

What is hair cell regeneration, you may ask ?

Ok, hair cell regeneration is a research where different doctors or scientists were able to observe that the damaged hearing hair cells of birds were regenerated. Thus they are trying to see if they can apply the same thing to humans. That is to try to regenerate the damaged hair cells of those with a hearing loss, to try to enable them to regain their hearing back.

Admittedly some centers or facilities do need more funds in order to speed up their research or progress. Perhaps, it would be helpful for these centers to have more media exposure of the topic on hair cell regeneration. Hoping that an increased awareness of such research could lead to more funds for these centers.

For instance, there is this research center shown below:

http://depts.washington.edu/hearing/initiative.html

So, where could we go from here ? Hope to hear from you soon. I'd appreciate it. Thanks in advance !

<--- End of e-mail --->

** HHIssues **

[This message has been edited by HHIssues (edited 07-23-2001).]

[This message has been edited by HHIssues (edited 07-23-2001).]

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Kevin
unregistered
posted 07-28-2001 04:15 PM           Edit/Delete Message
I got very happy when I found this forum - especially this section which contains something that I've been dreaming of the recent years.
I suggest we make a worldwide e-mail contact list that provides news and makes searching for grants for this project more effective. What do you think about this?

Greetings
Kevin

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HHIssues
Member
posted 07-30-2001 05:32 PM     Click Here to See the Profile for HHIssues     Edit/Delete Message
Hi Kev,

Welcome aboard ! Got this information from a friend that it seems that the following German Venture capital funds said they have funded Otogene's research work. These are the English versions of their web sites

TFG Capital

http://www.tfg.de/en/index2.php3

BMP Capital

http://www.bmp.com

Wellington Partners

http://www.wellington.de/de/portfolio.phtml

Actually, it's the research from the University of Washington that keeps claiming that they need more funds:

http://depts.washington.edu/hearing/initiative.html

** HHIssues **


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HHIssues
Member
posted 08-05-2001 10:47 AM     Click Here to See the Profile for HHIssues     Edit/Delete Message
Hello everyone,

Here's an interesting article from the House Ear Institute, titled "The Challenge of Hair Cell Regeneration":

http://www.hei.org/research/projects/cmb/haircellchall.htm

** HHIssues **

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Bob
Member
posted 08-14-2001 12:26 AM     Click Here to See the Profile for Bob     Edit/Delete Message
Greetings everyone,

In the new September issue of Popular Science magazine on page 39 there is an article on a new treatment for sudden hearing loss Titled "Now Hear This" This is not necessarily related to hair cell regeneration but the delivery system mentioned is new and would probably be applied for other treatments to the inner ear.

Sincerely,
Bob

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Kevin
unregistered
posted 08-17-2001 01:06 PM           Edit/Delete Message
Dear Bob,

would you mind posting the article here? I'm from Denmark and therefore I'm not able buying the magazine.

Greetings
Kevin

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Bob
Member
posted 08-17-2001 08:01 PM     Click Here to See the Profile for Bob     Edit/Delete Message
Hi Kevin,

Sorry about not posting the article but the september issue has not yet been posted to their web page. The web page is www.popsci.com and I would imagine that the september issue will be posted within a couple weeks.

Sincerely,
Bob

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HHIssues
Member
posted 08-25-2001 05:02 PM     Click Here to See the Profile for HHIssues     Edit/Delete Message
Here's a list of Labs or Centers that's working on Hair cell regeneration that I know of. If you know of any other that's not on the list. Let me know and I'll add it to the list. Thanks !

Research
http://www.bris.ac.uk/Depts/Physiology/Research/Hearing/hearingresearch.html

Expression profiles of auditory hair cells.
http://hg.wustl.edu/lovett/projects/nohr/index.html

Neuroscience Faculty: J.Corwin
http://www.med.virginia.edu/medicine/basic-sci/neurosci/corwin.html

Research Areas
http://www.medoto.unimelb.edu.au/research/

HRC RESEARCH AREAS
http://www.bu.edu/hrc/resareas.html

hearing initiative
http://depts.washington.edu/hearing/initiative.html

Home Page
http://wings.buffalo.edu/faculty/research/chd

Otogene AG
http://www.otogene.com/www/framesets/initial_frames.htm

Dr Corné Kros
http://www.bris.ac.uk/Depts/Physiology/Postgrad/ck.htm

** HHIssues **

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HHIssues
Member
posted 09-03-2001 04:53 PM     Click Here to See the Profile for HHIssues     Edit/Delete Message
Here's another one to add to the list:

University of Pennsylvania Health System http://www.med.upenn.edu/news/News_Releases/sept96/hair.html

Anyone out there know of any others to add to the list ?

** HHIssues **

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Sirisha
Member
posted 09-07-2001 11:28 AM     Click Here to See the Profile for Sirisha     Edit/Delete Message
Hi ALL,

My name is Sirisha. I am a mom for a 4 year old boy who has hearing loss in both of his ears. He is doing great with his hearing aids on and making wonderful progress in his school. My dream is to see my little boy hearing normally, just like me.
I am a member of other hearing loss message boards and I got lot of useful information from HHIssues. Thanks to him.
I will be the happiest person in the world, if my sons hearing loss is cured by any of the doctors. I cannot wait to see my son hearing normally.
I read all of your postings about Hair cell regeneration, etc. My support and help will be always with you. Please let me know, if I can do anything on this issue.

Thank You,
Sirisha.

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Kevin
unregistered
posted 09-11-2001 07:16 AM           Edit/Delete Message
I've been talking to a Danish professor today about all this (I'm from Denmark like I mentioned in another message). He told me that they already are able to reproduce hair cells, but the problem is that they can't reproduce nerves which are to be connected to these. He believed that this problem would take a few generations to solve, but I think this is just a way to make patients calm down and don't make them hope more than reality allows...yet.

That's just what I wanted to share with you.

Greetings
Kevin

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HHIssues
Member
posted 09-13-2001 10:23 AM     Click Here to See the Profile for HHIssues     Edit/Delete Message
Hi Kevin,

What's this doctor's name ? Where does he practice ? And does he have a website ? Maybe, I could see if I could look up some information on it throughout the Internet. What do you think ?

Sincerely,
--Dan

** HHIssues **

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Kevin
unregistered
posted 09-15-2001 02:57 PM           Edit/Delete Message
Dear Dan,

His name is K.O. Nielsen and he pratices at the Hospital of Soenderborg, which is placed in Southern Jutland, Denmark. As far as I know he doesn't have a website, but it's surely worth a try. I hope you'll find something.

Greetings,
Kevin

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